2019年10月14日下午16点，应william威廉亚洲官方邀请，日本大阪大学Nobuaki Kambe（神户宣明）教授在化学馆321会议室做了题为 “Carbon-Carbon Bond Forming Reactions Catalyzed by Transition Metal Ate Complexes ”的学术报告。此次报告由william威廉亚洲官方余达刚教授主持， Jason Chruma教授、曾小明教授、董顺喜教授和付海燕教授等老师及学生参加了此次报告。
在此次报告中，Kambe教授首先从四大偶联反应出发，引出了以B，Mg，Zn，Ti，Sn等试剂做亲核试剂，通过各种过渡金属催化的不同类型的C(sp2)-C(sp2), C(sp3)-C(sp2), C(sp3)-C(sp3)交叉偶联反应。随后，在该基础上，Kambe教授讲解了他们课题组以Ni, Co, Pd, Rh, Fe与双烯形成的Ate复合物为催化剂，高效构筑C-C键的系统工作。利用该策略，Kambe教授实现了对天然产物和药物分子的修饰，并对反应机理也进行了系统深入的研究。整场报告内容丰富，Kambe教授讲解清晰，由浅入深，形象生动地向我们展示了各种过渡金属Ate复合物催化C-C成键反应在有机合成的应用以及在复杂分子合成中的巨大潜能。在随后的自由提问环节，在座师生与Kambe教授进行了深入地讨论交流，大家获益匪浅。报告在全场师生热烈的掌声中落下了帷幕，结束后部分老师与Kambe教授进行了合影留念。
Prof. Nobuaki Kambe教授的个人简介：
Prof. Kambe got his B.S. and Ph.D. from Osaka University from 1972 to 1981. Then he worked as assistant professor in Osaka University. From 1982 to 1984, he did postdoctoral studies in Colorado State University, USA. Then he was promoted to associate professor in 1989 and full professor in 1999 in Osaka University. Now he is a guest professor of the Institute of Scientific and Industrial Research (ISIR) in Osaka University.
His main research areas are synthetic organic chemistry, organometallic chemistry, and physical organic chemistry. He developed various synthetic reactions using unique chemical reactivities of heavy heteroatom elements and/or transition metals. Particularly his current interests include carbon-carbon bond forming reactions on sp3-carbon centers catalyzed by first low transition metals such as Fe, Co, Ni, and Cu. He has published more than 200 papers with H-index of 34. He is a recipient of many prestigious awards and honors, including Chemical Society of Japan (CSJ) Award (2016), The Japan Petroleum Institute Awards (2016) and so on.
